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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 1, Issue 4 (2012)

In-Vitro Thrombolytic and Anti-inflammatory Activity of Swertia Chirata Ethanolic Extract.

Author(s):

Mohammad Shahadat Hossain*, Mohammad Ehsanul Hoque Chowdhury, Sumana Das and Imtiaz Uddin Chowdhury

Abstract:
Ethanol extract of of Swertia chirata was assessed for its thrombolytic, anti-inflammatory activity and phytochemical screening. In vitro anti-inflammatory activity was evaluated using albumin denaturation. Aspirin was used as a standard drug for the study of anti-inflammatory activity. The ethanol extract of Swertia chirata showed mean inhibition of protein denaturation 45.31±0.000576 whereas, for control group it was found to be 50.00±0.00177. In thrombolytic activity using in vitro clot lysis assay method, the crude ethanol extract was found to have significant, thrombolytic test showed a maximum effect of 40.38% while the standard streptokinase showed 69.35.

Pages: 99-104  |  2773 Views  451 Downloads


Journal of Pharmacognosy and Phytochemistry Journal of Pharmacognosy and Phytochemistry
How to cite this article:
Mohammad Shahadat Hossain*, Mohammad Ehsanul Hoque Chowdhury, Sumana Das and Imtiaz Uddin Chowdhury. In-Vitro Thrombolytic and Anti-inflammatory Activity of Swertia Chirata Ethanolic Extract.. J Pharmacogn Phytochem 2012;1(4):99-104.

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