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Journal of Pharmacognosy and Phytochemistry

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Journal of Pharmacognosy and Phytochemistry

Vol. 3, Issue 4 (2014)

In vitro antioxidant activity of extracts of the root Cochlospermum planchonii Hook. f. ex. Planch (Cochlospermaceae)

Author(s): Yeo Sounta Oumar, Guessennd Kouadio Nathalie, Meité Souleymane, Ouattara Karamoko, Bahi Gnogbo Alexis, N’Guessan Jean David and Coulibaly Adama
Abstract: In the present study, we have evaluated the antioxidant activity of four root extracts of Cochlospermum planchonii successively obtained by the solvent extraction method of increasing polarity. These are Dichloromethane extracts (EDCm), Acetatic (EACe), Ethanolic (EEth 96 %) and Aqueous (EAq). The determination of total phenols and total flavonoids by the colorimetric method showed that respectively the EEth 96% contains 476 ± 1.15 mg GAE/g of extracts and EACe have 24.63 ± 0.28 mg QE/g of extracts. In addition, evaluation of antiradical power extracts towards the DPPH confirms that EEth 96% and EACe are also the most active; with IC50 respectively, of the order of 01.83 ± 0.74 and 03.7 ± 0.98 mg / mL compared to vitamin C (01.25 ± 0.02 mg / mL) standard used as reference molecule. Furthermore, testing the ability of chelating iron ions to extract by EEth 96% better with an IC50 in the range of 03.42 ± 0.14 mg / mL as vitamin C to IC50 = 04, 08 ± 0.01 mg / mL. Similarly, the EACe, EDCm and EAq have shown good chelators, but less active than vitamin C. In addition, the EACe, EEth 96 % and EAq themselves have so good reducing the ferric ion to ferrous ion respectively Concentrations Effective (EC50) of approximately 16.80 ± 0.06; 06.50 ± 0.03 and 22.50 ± 0.06 mg / mL.
Pages: 164-170  |  1002 Views  11 Downloads
How to cite this article:
Yeo Sounta Oumar, Guessennd Kouadio Nathalie, Meité Souleymane, Ouattara Karamoko, Bahi Gnogbo Alexis, N’Guessan Jean David and Coulibaly Adama. In vitro antioxidant activity of extracts of the root Cochlospermum planchonii Hook. f. ex. Planch (Cochlospermaceae). Journal of Pharmacognosy and Phytochemistry. 2014; 3(4): 164-170.
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