Author(s):

Ahmed Jibrin Uttu, Mohammed Sani Sallau, Hamisu Ibrahim, Mubarak Balarabe Dambatta, Abdullahi Yunusa Idris

Abstract: The medicinal plant Glossonema boveanum (Decne) is known locally for its medicinal value. Preliminary phytochemical screening of the extracts from stem bark using standard procedures showed positive test for alkaloids, carbohydrates, steroids, triterpenes, cardiac glycosides, saponins, tannins and flavonoids. The antimicrobial activity against Staphylococus aureus, Bacillus subtilis, Streptococcus agalactiae, Shigella dysenteriae, Salmonella typhii, Escherichia coli, and Candida albicans was carried out on methanol, ethyl acetate and n-hexane extracts using Agar well diffusion method and broth dilution method. The extracts were found to be effective against all the pathogens except S. agalactiae and C. albicans. Minimum Inhibitory Concentration (MIC) results revealed that Ethyl acetate and Methanol extracts inhibits the growth of the tested microorganisms and was as low as 3.125µg/mL. Our findings showed that the extracts from the stem bark of G. boveanum contain potential antimicrobial compounds worthy of further investigation. This claim supports the ethno medicinal usage of the plant.

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