The hydro-ethanolic crude extract of stem bark contains several classes of secondary metabolites such as polyphenols, tannins, flavonoids, terpenoids, alkaloids, saponins mucilage, coumarin, cardiac glycosides, etc. The partition of this crude extract with ethyl acetate resulted into the isolation of condensed tannins. The determination of condensed tannins via total proanthocyanidin assay yielded a concentration of 0.865 mg EC / mL with an optical density of 0.558. The minimum inhibitory concentrations (MIC) ranged from 1.25 to 2.5 mg / mL while the minimum bactericidal or fungicidal concentrations (MBC or MFC) ranged from 1.25 mg / mL to 5 mg / mL. The best bactericidal and absolute fungicidal activities were respectively recorded on Staphylococcus aureus and Candida krusei and Candida parapsilosis with results (MBC/ MIC or MFC / MIC = 1). A relatively bactericidal activity good was also recorded againat Shigella flexneri (MBC / MIC = 2). On the other hand, condensed tannins exhibited bacteriostatic or fungistatic activitities on Salmonella enterica, Shigella flexneri, Escherichia coli and Candida albicans with (MBC / MIC = 4).

This study has also led to isolation of a proanthocyanidol. On the basis of the antimicrobial activities of condensed tannins in this study, it can be concluded that condensed tannins from Erytrhophleum guineensis effectively exhibit antimicrobial properties and this may justify the use of this plant in the treatment of diarrhea caused by food poisoning.