Author(s):

RC Patil, CP Kulkarni and Ashu Pandey

Abstract:
In the present study the aqueous, methanol, ethanol and acetone extract of Tinospora cordifolia, Azarchita indica and Ocimum santum leaves extract were screened for the presence of phytochemical components and tested for antibacterial activity against Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia, Enterobacter aerogenes, Pseudomonas aeruginosa, Salmonella typhimurium, Salmonella typhi, Staphylococcus epidermidis and Proteus vulgaris. Results revealed the presence of anthraquinones, alkaloids, saponins, tannins, glycosides and phenolics. The acetone extracts had wide range of antibacterial activity against bacterial pathogens than the ethanol and methanol extract, whereas aqueous extract were slightly higher antibacterial activity as ethanol extract. Antibacterial activity of various extract of leaves of Tinospora cordifolia, Azarchita indica and Ocimum santum would lead to the establishment of some compounds that could be used to formulate new and more potent antimicrobial drugs of natural origin. Further work is being carried out to isolate and identify the active constituents of the plants responsible for antibacterial activity.

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