Author(s):

Abubakar E Mazadu, Magnus Ezihe and Bala MB

Abstract: The roots and steam barks of Ceiba pentandra was prepared by extracting 100_g of the crude sample using the hot soxhlet extraction with n-hexane, ethyl acetate, acetone, methanol and water sequentially in order of their polarity index. The extracts were tested against some clinical isolates of Eschericia coli, Staphylococcus aureus, Aspergillus niger and Candida albicans. The results showed that water stem extracts of Ceiba pentandra produces high activity with 15.00ug/ml, and the methanol roots of extracts of Ceiba pentandra A(R)B, M(R)A and W(R)A had the least activity of 0.00, 0.0 fungal activity. Streptomycin was used as the standard for the antibacterial activity while Fulcin was used as the standard for the antifungal activity. The antimicrobial activity of the roots and stem barks of Ceiba pentandra justifies the claims by the traditional healers that the roots and stem barks of the plants in used to cure different ailments.

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