Author(s):

Dr. Piyush M Maurya

Abstract: The methanol extract of achyranthes aspera linn. (family- amaranthaceae) the herb changed into studied for its phytochemical and a few pharmacological activities. The take a look at of the herb extracts indicated the presence of flavonoids, tannins, saponins, and alkaloids. The pharmacological have a look at includes thrombolytic and cytotoxic pastime. They showed substantial cytotoxic impact in brine shrimp lethality bioassay wherein the plant extracts exhibited lc50 =3.80µg/ml and lc90=7.04µg/ml (after 18 hour); lc50 =3.31µg/ml and lc90 =6.36µg/ml (after 21 hour); lc50 =2.18µg/ml and lc90 =5.29µg/ml (after 24 hour). This look at gave a massive indication to using the plant extract as an ability supply for cytotoxic compounds. Inside the thrombolytic hobby of widespread was determined seventy 6.08% and for a. aspera was 36.49%, which shows mild thrombolytic activity. Based at the findings of thrombolytic and toxicological pastime, we can say that achyranthes aspera may additionally incorporate some novel compounds that own strong anti-mutagenic activity and clot lysis assets.

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