Volume 4, Issue 2

 

Antifungal activity of the extract of Andrographis paniculata and Andrographolide

 

Author: Eugene Sebastian J Nidiry, Girija Ganeshan, A.N. Lokesha

Abstract: Antifungal activity assay of the methanol extract of the aerial parts of the plant Andrographis paniculata revealed that it exhibits mycelial growth inhibition of Fusarium solani and spore germination inhibition of Alternaria solani. Pure andrographolide present in the methanol extract also exhibited spore germination inhibition of A. solani. Quantitative estimation of andrographolide in the methanol extract by HPLC revealed that it had 6.82% andrographolide in it. This is probably the first report on the antifungal activity of andrographolide.

 

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