Journal of Pharmacognosy and Phytochemistry
Vol. 8, Issue 4 (2019)
A study on in vitro anti- inflammatory activity of silver nanoparticles synthesized from Dodonaea angustifolia leaf extract
Author(s):
N Revathi and TS Dhanaraj
Abstract:
This paper presents an empirical analysis on the use of aqueous extract of
Dodonaea angustifolia for the production of silver nanoparticles (AgNPs) from aqueous silver nitrate. The
Dodonaea angustifolia leaf extract, AgNPs and Diclofenac sodium at different concentrations was incubated with egg and Bovine serum albumin in controlled experimental conditions and subjected to determination of absorbance to assess the anti-inflammatory property. Diclofenac sodium was used as the reference drug. The present findings exhibited a concentration dependent inhibition of protein denaturation by
Dodonaea angustifolia extract and AgNPs. The effect of AgNPs was found to be high when compared with the
Dodonaea angustifolia extract and near to the diclofenac sodium. From the present study it can be concluded that AgNPs possessed marked
in vitro anti-inflammatory effect against the denaturation of protein.
Pages: 1878-1881 | 1242 Views 541 Downloads
N Revathi and TS Dhanaraj. A study on in vitro anti- inflammatory activity of silver nanoparticles synthesized from Dodonaea angustifolia leaf extract. J Pharmacogn Phytochem 2019;8(4):1878-1881.