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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 13, Issue 4 (2024)

Solvent-based comparative analysis of antioxidant and antimicrobial activities in Sterculia urens Extracts

Author(s):

Ayeshabi Saeed Haji, Siddharth Rajendra Maurya and Dr. Nisha Shah

Abstract:

The present study explores the antioxidant and antimicrobial properties of Sterculia urens powder extracts obtained using different solvents (ethyl acetate, chloroform, ethanol, and distilled water) and extraction methods (cold and hot). Phytochemical analysis identified several bioactive compounds including steroids, terpenoids, flavonoids, phenols, cardiac glycosides, coumarins, and saponins, with the composition varying based on the solvent and extraction technique employed. Antioxidant assays (DPPH, FRAP, ABTS) demonstrated significant radical scavenging capabilities, particularly in ethanol and ethyl acetate extracts, with the highest activities observed in the hot ethanol extract. Total phenolic and flavonoid contents correlated with antioxidant activity, highlighting their contributions to free radical neutralization. The antimicrobial activity was evaluated using the agar well diffusion method against both Gram-positive and Gram-negative bacteria. Notably, the ethyl acetate extracts displayed significant antimicrobial activity, especially against Streptococcus pyogenes, Escherichia coli, and Bacillus subtilis. These results indicate that S. urens extracts, particularly those derived using hot ethanol and ethyl acetate, are potent sources of antioxidants and exhibit considerable antimicrobial efficacy. This study underscores the potential application of S. urens extracts in pharmaceutical and food industries, highlighting their role as natural preservatives and therapeutic agents.

Pages: 289-295  |  143 Views  55 Downloads


Journal of Pharmacognosy and Phytochemistry Journal of Pharmacognosy and Phytochemistry
How to cite this article:
Ayeshabi Saeed Haji, Siddharth Rajendra Maurya and Dr. Nisha Shah. Solvent-based comparative analysis of antioxidant and antimicrobial activities in Sterculia urens Extracts. J Pharmacogn Phytochem 2024;13(4):289-295. DOI: 10.22271/phyto.2024.v13.i4d.15019

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