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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 13, Issue 5 (2024)

LC-MS/MS and tandem MS/MS identification of chemical compounds of the stem bark of Acacia macrostachya (Mimosaceae)

Author(s):

Hamidou Têeda Ganamé, Yssouf Karanga, Richard Wamtinga Sawadogo and Issa Tapsoba

Abstract:

The main objective of this work was to identify chemical compounds of biological interest in the methanol extract of Acacia macrostachya stem bark using High-Performance Liquid Chromatography coupled with tandem Mass Spectrometry (HPLC-MS/MS) and Global Natural Product Social Molecular Networking (GNPS) databases. A total of seven (07) molecules from four families of secondary metabolites such as Kaempferol-3-O-rutinoside, kaempferol, epicatechin, epicatechin-3-O-gallate, bergaptol-O-β-D-glucopyranoside, 3-hydroxyurs-12-en-28-oic acid and kaempferid were identified The presence of these compounds in the extract could be responsible of the anti-diabetic and anti-cancer properties of this extract which were reported in our previous investigations.

Pages: 144-151  |  214 Views  76 Downloads


Journal of Pharmacognosy and Phytochemistry Journal of Pharmacognosy and Phytochemistry
How to cite this article:
Hamidou Têeda Ganamé, Yssouf Karanga, Richard Wamtinga Sawadogo and Issa Tapsoba. LC-MS/MS and tandem MS/MS identification of chemical compounds of the stem bark of Acacia macrostachya (Mimosaceae). J Pharmacogn Phytochem 2024;13(5):144-151. DOI: 10.22271/phyto.2024.v13.i5b.15067

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