Halime Mahamat Alifa, Martial Lamere Litchang, Severin Mbaihougadobe, Abel Mbaiogaou, Mahamat Abakar Ali and Yaya Mahmout

Background and Objective: Acute respiratory infections pose serious problems of health in infants over the world. In rural Chadian areas where conventional medicine is not often available, the first days of an infant's life are those where the risk of death is too high. The present work focused on the inventory of some plants used for the treatment of respiratory infections in infants in Sarh, southern Chad. Therefore, the phytochemical and the antibacterial analyses were determined.
Materials and Methods: Twenty five volunteers for the survey were interviewed in order to collect information concerning the use of plants, the methods of preparation and the route of administration. Phytochemical analysis using coloration tests was performed on the extracts of the five most cited species. Antibacterial activity of the two representative plant extracts was determined using Agar plate dilution method.
Results: A total of 26 species have been identified. Among the species listed, five are the most cited; such as: Guiera senengalensis, Piliostigma reticulatum, Eucalyptus camaldulensis, Mitragina inermis and Leptadenia hastata. Phytochemical screening carried out on the five selected plants, showed the presence of alkaloids, phenolics, flavonoids, saponins, quinones and triterpenes/steroids. The study on antibacterial activity showed that G. senegalensis extract showed low to moderate activity on bacteria, whereas P. reticulatum extract showed low antibacterial activity against Pseudomonas aeruginosa only.
Conclusion: Due to the various chemical compositions of plants, processes combining species could be effective against respiratory infections. These results show that combined species could be used as potential agents for the development of the pharmaceutical drugs. 
 

DOI: 10.22271/phyto.2024.v13.i6d.15193

Pages: 285-289  |  104 Views  46 Downloads