Ejiofor InnocentMary Ifedibaluchukwu, Ajasigwe Innocent Chijioke, Ogbue Cyril Onyeka and Ibe Chioma Ifeoma

Young children, women who are pregnant or just gave birth, and girls who are menstruation are all at risk for anemia, which is a serious public health issue. A common medicinal plant in Nigeria, Justicia carnea, is thought to have blood-boosting properties. This study assesses how its ethyl acetate leaf extract affects hemolytic anemia in albino rats caused by phenylhydrazine. A normal control, a negative control, and three treatment groups that received either 100 mg/kg of ferrous fumarate or 100 mg/kg or 500 mg/kg of Justicia carnea extract were the five groups of rats. All groups except the control group experienced anemia from phenylhydrazine (40 mg/kg). Following a 20-day course of treatment, the treated rats' hemoglobin (Hb), packed cell volume (PCV), and red blood cell (RBC) count all markedly increased. The study suggests Justicia carnea can reverse anaemia, likely due to its phytochemicals (tannins, flavonoids, proteins). These findings highlight its potential in anaemia treatment.

DOI: 10.22271/phyto.2025.v14.i1e.15262

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