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Journal of Pharmacognosy and Phytochemistry
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Journal of Pharmacognosy and Phytochemistry

Vol. 14, Issue 2 (2025)

Evaluation of phytochemical screening and DPPH free-radical scavenging activity of leaves extract of Pouzolzia zeylanica (L.) Benn (Family: Urticaceae)

Author(s):

Most. Nazma Parvin

Abstract:

Pouzolzia zeylanica (L.) Benn., a perennial herbaceous medicinal plant from the Urticaceae family, is commonly found along roadsides throughout Bangladesh and is widely distributed across both Asia and Australia. This plant is traditionally used to treat a variety of ailments, including diarrhea, indigestion, infantile malnutrition, urinary difficulties, and injuries from falls. The aim of the current study was to analyze the phytochemical constituents and assess the in vitro antioxidant activity of the methanol extract of Pouzolzia zeylanica leaves. The antioxidant activity was evaluated using the 1, 1-diphenyl-2-picryl-hydrazyl (DPPH) free radical scavenging method. The extract was found to contain various phytochemicals, including carbohydrates, tannins and phenolic compounds, saponins, alkaloids, flavonoids, gums and mucilages. In the DPPH assay, the leaves extract exhibited notable antioxidant activity, with an IC50 value of 296.10±0.83 μg/mL, compared to ascorbic acid, which had an IC50 of 5.25±0.27 μg/mL. In conclusion, the findings suggest that the methanol extract of Pouzolzia zeylanica leaves exhibit free radical scavenging potential, indicating its use as a natural antioxidant.

Pages: 578-582  |  109 Views  58 Downloads


Journal of Pharmacognosy and Phytochemistry Journal of Pharmacognosy and Phytochemistry
How to cite this article:
Most. Nazma Parvin. Evaluation of phytochemical screening and DPPH free-radical scavenging activity of leaves extract of Pouzolzia zeylanica (L.) Benn (Family: Urticaceae). J Pharmacogn Phytochem 2025;14(2):578-582. DOI: 10.22271/phyto.2025.v14.i2g.15333

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