Pranali D. Tekade, Avinash M. Deshmukh and Deepali J. Amale
Ayurveda, the holistic science, suggests the unique principles of Tridosha, Dhatu, and Mala for maintaining a healthy body. Dhatu nourishes the body, supplies nutrients to other vital tissues through Strotasa, supports the body, and keeps the body healthy. During the formation of Asthi Dhatu, Vata creates spaces in bones. These spaces are occupied by the nourishing tissue known as Medas, which is referred to as Majja or bone marrow. Majja Dhatu nourishes the body, strengthens the body, fills bones, and nourishes or helps in the production of Shukra Dhatu. Due to Pragyaparadha, Asatmyendriyarth Samyoga, and Parinama, the balance of Doshas, Dhatus, and Malas is disrupted, leading to an imbalance in the body's homeostasis. Asthipuranam is done by Majja Dhatu. That’s why Majja Kshaya takes place due to the disturbed equilibrium of Tridosha, then Asthi Dhatu is most affected. Pakshaghata is a Vata Nanatmaja disorder categorized as Krichasadhya (difficult to cure). It presents with symptoms such as Ruja (pain), Vakstambha (stiffness of speech), and is classified as a type of cerebrovascular disease. In Pakshaghat, mainly gait is affected in the long term, and sandhi is closely related to the majja dhatu.
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