Pharmacognosy

Journal of Pharmacognosy and Phytochemistry

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Journal of Pharmacognosy and Phytochemistry

Vol. 2, Issue 1 (2013)

Phytochemical properties, total antioxidant status of acetone and methanol extract of Terminalia arjuna Roxb. bark and its hypoglycemic effect on Type-II diabetic albino rats.

Author(s): Chandan Kumar*, Raj Kumar, Shamshun Nehar
Abstract: In the present study, acetone and methanol extract of T. arjuna Roxb. bark was evaluated for its phytochemical properties and antioxidant status by FRAP method. The result indicated that tannin, alkaloid, triterpenoid, flavonoid, phytosteroids and saponin are present in both the acetone and methanol extract. Total antioxidant status was found to be significantly (P˂0.01) higher in acetone extract (212.5±11.55 µM) as compared to methanol extract (35.50±4.70 µM). This indicates higher antioxidative property of T. arjuna bark acetone extract in comparison to methanol extract and selected for in vivo study. In vivo study, showed protective effect of acetone extract of T. arjuna bark towards blood glucose, oral glucose tolerance (OGTT) and insulin tolarence test in STZ treated rats. Feeding 500 mg/kg bw arjuna bark extract to rats showed significantly (P
Effect of Acetone Extract of Terminalia arjuna bark and Performance of all Groups of rats for Oral Glucose Tolerance Test (OGTT) on 8th week of Experiment. (Values are Mean± S.E.M. of three Experiments, Means with Different Letters are Significantly Different at (P<0.05).
Fig.: Effect of Acetone Extract of Terminalia arjuna bark and Performance of all Groups of rats for Oral Glucose Tolerance Test (OGTT) on 8th week of Experiment. (Values are Mean± S.E.M. of three Experiments, Means with Different Letters are Significantly Different at (P<0.05).
Pages: 199-208  |  1164 Views  11 Downloads
How to cite this article:
Chandan Kumar*, Raj Kumar, Shamshun Nehar. Phytochemical properties, total antioxidant status of acetone and methanol extract of Terminalia arjuna Roxb. bark and its hypoglycemic effect on Type-II diabetic albino rats.. J Pharmacogn Phytochem 2013;2(1):199-208.
Journal of Pharmacognosy and Phytochemistry