Pharmacognosy

Journal of Pharmacognosy and Phytochemistry

  • Printed Journal
  • Indexed Journal
  • Refereed Journal
  • Peer Reviewed Journal
Login

NAAS Rating: 5.21

updates
NAAS Rating: 5.21 new

Journal of Pharmacognosy and Phytochemistry

Vol. 2, Issue 4 (2013)

Sedative and Cytotoxic Properties of the leaf Extract of Desmodium paniculatum

Author(s): Mohammad Mamun Ur Rashid1*, Humayun Kabir1, Mohammed Aktar Sayeed2, Rashedul Alam1, Mohammad Fazlul Kabir1
Abstract: The present study was done to investigate the sedative and cytotoxic properties of methanol extract of Desmodium paniculatum Leaves. Sedative activity was evaluated by using hole cross, open field and thiopental sodium-induced sleeping time methods in swiss albino mice at 400 mg/kg body weight dose orally and the extract was evaluated by in-vitro brine shrimp lethality bioassay for investigating cytotoxic activity. The extract decreased the locomotor activity of mice in hole cross, open field test and minimize the onset of sleep and maximized the duration of sleeping time significantly (p
Pages: 63-67  |  1194 Views  12 Downloads
How to cite this article:
Mohammad Mamun Ur Rashid1*, Humayun Kabir1, Mohammed Aktar Sayeed2, Rashedul Alam1, Mohammad Fazlul Kabir1. Sedative and Cytotoxic Properties of the leaf Extract of Desmodium paniculatum. J Pharmacogn Phytochem 2013;2(4):63-67.
Journal of Pharmacognosy and Phytochemistry