Author(s): Ezekwe, Ahamefula Sunday., Elekwa, Ify., Osuocha, Kelechi Uzoma.

Abstract: The present study was designed to evaluate some selected biochemical effects of unripe pulp of Carica papaya on alloxan induced diabetes in rats. Animals weighing (160-200 g) were divided into three (3) groups of 10 animals each; Group I (normal control), Group II (diabetic control) and Group III (test control). Diabetes was induced in albino rats by intraperitoneal injection of alloxan monohydrate at a single dose of 120 mg/kg body weight into groups II and III respectively. Animals in groups I and II received normal rat feeds while animals in group III were fed with unripe pulp of Carica papaya for a period of 28 days. Body weight and glucose levels were measured on days 0, 7, 14, 21, and day 28. It was observed in this study that there was a significant reduction of Glycated hemoglobin in the test group when compared with the induced control (diabetic rats) and normal control group (P