Pharmacognosy

Journal of Pharmacognosy and Phytochemistry

  • Printed Journal
  • Indexed Journal
  • Refereed Journal
  • Peer Reviewed Journal
Login

NAAS Rating: 5.21

updates
NAAS Rating: 5.21 new

Journal of Pharmacognosy and Phytochemistry

Vol. 3, Issue 2 (2014)

Characterization of galactose rich fucoidan with anticoagulation potential isolated from Turbinaria decurrens Bory de Saint-Vincent occurring along the coast of Gulf of Mannar (Pamban), India

Author(s): N.Shanthi, T.Eluvakkal and K.Arunkumar
Abstract: Fucoidan is a group sulfated hetero polysaccharide found in the cell wall of some members of Phaeophyceae. Two fractions of fucoidan one with low molecular weight (LMW) with> 3500 Da and another with high molecular weight (HMW) with <3500 Da showed promising anticoagulation activity under in vitro APTT assay were isolated from the brown seaweed Turbinaria decurrens occurring along the coast of Pamban (Gulf of Mannar), India. Fucoidan isolated using DEAE Cellulose column was characterized by FTIR spectroscopy dominating galactose followed by fucose, mannose and glucose. But more anticoagulation activity was recorded in HMW A1H fraction than LMW fraction isolated from the brown seaweed Turbinaria decurrens. The anticoagulation activity was an increased with increase in the sulphate content in the fucoidan.
In vitro anticoagulation assay of fucoidan fractions AL1(LMW) and AH1(HMW) isolated from the brown seaweed Turbinaria decurrens collected along the coast of Gulf of Mannar( Pamban), Indi
Fig.: In vitro anticoagulation assay of fucoidan fractions AL1(LMW) and AH1(HMW) isolated from the brown seaweed Turbinaria decurrens collected along the coast of Gulf of Mannar( Pamban), Indi
Pages: 132-137  |  1175 Views  9 Downloads
How to cite this article:
N.Shanthi, T.Eluvakkal, K.Arunkumar. Characterization of galactose rich fucoidan with anticoagulation potential isolated from Turbinaria decurrens Bory de Saint-Vincent occurring along the coast of Gulf of Mannar (Pamban), India. J Pharmacogn Phytochem 2014;3(2):132-137.
Journal of Pharmacognosy and Phytochemistry