Pharmacognosy

Journal of Pharmacognosy and Phytochemistry

  • Printed Journal
  • Indexed Journal
  • Refereed Journal
  • Peer Reviewed Journal
Login

NAAS Rating: 5.21

updates
NAAS Rating: 5.21 new

Journal of Pharmacognosy and Phytochemistry

Vol. 4, Issue 1 (2015)

Cardioprotective and anti-inflammatory activities of a polyphenols enriched extract of Hibiscus sabdariffa petal extracts in wistar rats

Author(s): Abba Pacôme Obouayeba, Souleymane Meité, Lydie Boyvin, Dodehe Yeo, Tanoh Hilaire Kouakou, Jean David N’Guessan
Abstract: Hibiscus sabdariffa is a medicinal and food plant rich in phytochemical compounds which are the source of its biological properties. This study was conducted to assess its cardioprotective and anti-inflammatory proprieties. The study of the cardioprotective activity was made with 20 Wistar rats divided into four groups. The treatments were carried out via oral route and at single dose for one week. After injection of doxorubicin, blood samples were collected for the dosage of biochemical markers of cardiotoxicity (alanine aminotransferase, aspartate aminotransferase, creatine kinase MB and lactate deshydrogenase). The anti-inflammatory activity was also conducted with 20 Wistar rats divided into four groups. After administration of treatments via oral route, the volume of the legs of the animals was measured. The results had shown that the cardiotoxicity of doxorubicin observed in rats of group 2 was significantly different (P
Pages: 57-63  |  1302 Views  22 Downloads
How to cite this article:
Abba Pacôme Obouayeba, Souleymane Meité, Lydie Boyvin, Dodehe Yeo, Tanoh Hilaire Kouakou, Jean David N’Guessan. Cardioprotective and anti-inflammatory activities of a polyphenols enriched extract of Hibiscus sabdariffa petal extracts in wistar rats. J Pharmacogn Phytochem 2015;4(1):57-63.
Journal of Pharmacognosy and Phytochemistry