Vol. 4, Issue 4 (2015)
Assessment of the antimicrobial activity of the ethanolic extract of Phyllanthus emblica in combination with different classes of antibiotics against single and multi-drug resistant strains
Author(s): Nisrat Jahan, Salma Akter
Abstract: Medicinal plants have been served as a great source of medicine since the ancient era. Amla is indeed, the key ingredient in the popular ayurvedic recipe, Chyavanaprasha. More than anything, it may be called as "King of Rasayana" [rejuvenation]. The fruit is rich in quercetin, phyllaemblic compounds, gallic acid, tannins, flavonoids, pectin and vitamin C and also contains various polyphenolic compounds. A wide range of phytochemical components including terpenoids, alkaloids, flavonoids, and tannins have been shown to posses’ useful biological activities. Many pharmacological studies have demonstrated the ability of the fruit shows antioxidant, anticarcinogenic, antitumour, antigenotoxic, antiinflammatory activities, supporting its traditional uses. In this review, we have focused our interest on the antimicrobial potential of crude ethanolic extract of Phyllanthus emblica alone and in combination with 2 antibiotic drugs in 12 microorganism culture. The antimicrobial activity was evaluated by Disc diffusion method. The extract was assayed at 500µg/disc concentration with standard kanamycin disc against gram positive, gram negative and multi drug resistant strains. In view of its reported pharmacological properties and relative safety, P. emblica could be a source of therapeutically useful products.
How to cite this article:
Nisrat Jahan, Salma Akter. Assessment of the antimicrobial activity of the ethanolic extract of Phyllanthus emblica in combination with different classes of antibiotics against single and multi-drug resistant strains. J Pharmacogn Phytochem 2015;4(4):142-155.