Pharmacognosy

Journal of Pharmacognosy and Phytochemistry

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Journal of Pharmacognosy and Phytochemistry

Vol. 5, Issue 2 (2016)

Comparative HPLC analysis of emodin, aloe emodin and rhein in Rheum emodi of wild and in vitro raised plants

Author(s): Shagoon Tabin, R.C. Gupta, Gulshan Bansal, Azra. N. Kamili
Abstract: The plants are like microbiosynthetic factories having variety of compounds which are their secondary metabolites. These compounds mainly include alkaloids, glycosides, flavonoids, volatile oils, saponins, etc. with tremendous biological activities. The medicinal properties are attributed to the specific bioactive compound or combination of phytochemicals. Rheum species contains anthraquinone derivatives, anthronones and tannins, etc., in which anthraquinone derivatives including emodin, aloe-emodin, rhein, physcion, chrysophanol and their glucosides are the accepted important active components. The methods commonly used for the determination of the anthraquinone compounds in Rheum species are high performance liquid chromatography (HPLC). Aloe-emodin is a natural active compound present in the Rheum species. It has also been found that aloe-emodin has numerous biological properties including antiviral, antimicro­bial and hepatoprotective activities. Aloe-emodin has been reported to exhibit anticancer activity on neuroectodermal tumors, lung squamous cell carcinoma and hepatoma cells. Another compounds found in Rheum species are emodin, rhein, chrysaphanol, physicion etc.
Pages: 121-130  |  1574 Views  50 Downloads
How to cite this article:
Shagoon Tabin, R.C. Gupta, Gulshan Bansal, Azra. N. Kamili. Comparative HPLC analysis of emodin, aloe emodin and rhein in Rheum emodi of wild and in vitro raised plants. J Pharmacogn Phytochem 2016;5(2):121-130.
Journal of Pharmacognosy and Phytochemistry