Journal of Pharmacognosy and Phytochemistry
Vol. 5, Issue 5 (2016)
In Vitro Anti-inflammatory property and phytochemical content of methanol extract of Strychnos nux-vomica L (Seeds)
Author(s): Bhavya DK and Krishnamoorthy M
Abstract: The use of plants as medicine is an ancient practice common to all societies especially the Indian society. This practice continues to exist in the developing nations. It is on this basis that researchers keep on working with medicinal plants in order to produce the best medicines for physiological uses. The aim of present study was to isolate and identify bioactive compounds from the methanol extracts of Strychnos nux-vomica seeds using HPTLC profiling and GC-MS. HPTLC fingerprints scanned at 254 & 366 nm revealed the presence of phytoconstituents of highest concentration 39.64% & 65.35% respectively. Five constituents were eluted by GC-MS a major compound eluted at RT 19.119 mins was identified as 1-cyclohexylethyl ester of trifluoroacetic acid which accounted for 100%. The compounds were identified and confirmed by comparing their mass spectrum with the original spectrum obtained from the inbuilt libraries NIST-11. The methanol extract of S nux- vomica seeds showed significant anti-inflammatory activity.
How to cite this article:
Bhavya DK, Krishnamoorthy M. In Vitro Anti-inflammatory property and phytochemical content of methanol extract of Strychnos nux-vomica L (Seeds). J Pharmacogn Phytochem 2016;5(5):162-166.