Pharmacognosy

Journal of Pharmacognosy and Phytochemistry

  • Printed Journal
  • Indexed Journal
  • Refereed Journal
  • Peer Reviewed Journal
Login

NAAS Rating: 5.21

updates
NAAS Rating: 5.21 new

Journal of Pharmacognosy and Phytochemistry

Vol. 5, Issue 6 (2016)

Baccharis spicata (Lam) Baill: Polyphenol screening, determination of their antioxidant activity and their main polyphenolic metabolites

Author(s): Ignacio J Agudelo, Santiago A Isolabella, Rosana Filip, Marcelo L Wagner and Rafael A Ricco
Abstract: Baccharis spicata is a dioecious plant from South America. The quantitative variation of its polyphenolic compounds was studied in methanolic extracts of its vegetative and reproductive aerial organs. Leaves were found to be the organ with the highest polyphenol concentration. The main compounds have been characterized by thin layer chromatography and high performance liquid chromatography with standard compounds, and studies of structural elucidation were performed by UV-Visible spectrophotometry. The flavonoid rutin and the caffeoylquinic derivatives chlorogenic acid, and 3, 5; 3, 4 and 4, 5 dichlorogenic acids have been found. Studies of antioxidant activity were performed, obtaining a value of IC50 of 61.3µg/ml extract. This work sets a precedent in the study of this species and its possible therapeutic use in diseases related to the generation of oxidative stress.
Pages: 278-285  |  1229 Views  41 Downloads
How to cite this article:
Ignacio J Agudelo, Santiago A Isolabella, Rosana Filip, Marcelo L Wagner, Rafael A Ricco. Baccharis spicata (Lam) Baill: Polyphenol screening, determination of their antioxidant activity and their main polyphenolic metabolites. J Pharmacogn Phytochem 2016;5(6):278-285.
Journal of Pharmacognosy and Phytochemistry