Pharmacognosy

Journal of Pharmacognosy and Phytochemistry

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Journal of Pharmacognosy and Phytochemistry

Vol. 6, Issue 1 (2017)

Evaluation of antihypertensive activity of Sumbul-ut-Tib (Nardostachys jatamansi) in adrenaline induced dog’s blood pressure

Author(s): Mohd. Ashfaque, Nisar Ahmad, Zaheda Begum and Faizana Nasreen
Abstract: Background: Sumbul-ut-Tib has been used in Unani System of medicine since the time of Avicenna. He has described Jatamansi as one of the important cardiac drug in his book “Advia Qalbia”. The aim of this study was to determine the antihypertensive activity of Nardostachys jatamansi in dog’s blood pressure which is induced by adrenaline.
Materials and Methods: Antihypertensive activity of ethanolic extract of Sumbul-ut-Tib at the doses of 10 mg/kg. b.wt, 20 mg/kg b.wt. and 25 mg/kg b.wt. against adrenaline at the dose of 1 mcg/kg b.wt. in dogs.
Results: The test drug produced fall in B.P. was noted, fall in B.P. was same in doses of 10 mg/kg. b.wt, 20 mg/kg. b.wt, while with the dose of 25 mg/kg. b.wt. more fall in B.P. was noted i.e. 160 mm of Hg to 130 mm of Hg.
Conclusion: This result suggests that the jatamansi revealed hypotensive activity against adrenaline induced hypertension.
Pages: 93-95  |  1158 Views  27 Downloads
How to cite this article:
Mohd. Ashfaque, Nisar Ahmad, Zaheda Begum, Faizana Nasreen. Evaluation of antihypertensive activity of Sumbul-ut-Tib (Nardostachys jatamansi) in adrenaline induced dog’s blood pressure. J Pharmacogn Phytochem 2017;6(1):93-95.
Journal of Pharmacognosy and Phytochemistry