Vol. 6, Issue 5 (2017)
Anti-oxidant Constituents from Corydalis govaniana Wall and C. casimiriana Duthie and Prain ex Prain
Author(s): Ram Lal Shrestha and Achyut Adhikari
Abstract: Corydalis govaniana Wall. and C. casimiriana Duthie and Prain ex Prain., have been used in the treatment of syphilis, scrofula, cutaneous infections, along with diarrhea and dysentery. One tetrahydro-protoberberine type alkaloid, govaniadine (1); and six other alkaloids, caseadine (2), caseamine (3), protopine (4), stylopine (5), apocavidine (6), and fagarine I (7) were isolated from these two medicinal plants. Caseamine showed the best anti-oxidant (DPPH radical scavenging) activity (IC50 = 40.8 ± 0.9 µM). Govaniadine and caseadine showed moderate antioxidant activity (IC50 = 83.7 ± 1.7 µM), and IC50 = 75.7 ± 0.9 µM, respectively).
How to cite this article:
Ram Lal Shrestha, Achyut Adhikari. Anti-oxidant Constituents from Corydalis govaniana Wall and C. casimiriana Duthie and Prain ex Prain. J Pharmacogn Phytochem 2017;6(5):568-570.