Pharmacognosy

Journal of Pharmacognosy and Phytochemistry

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Journal of Pharmacognosy and Phytochemistry

Vol. 7, Issue 1 (2018)

Antiplasmodial activity and phytochemical screening of Landolphia heudelotii, Mitragyna ledermannii and Spathodea campanulata, three traditional plants

Author(s): Kipré Gueyraud Rolland, Offoumou Rostand M’Baï, Silué Kigbafori Dieudonné, Bouablé Guy Martial, Zirihi Guédé Noel and Djaman Allico Joseph
Abstract: Plant extracts contain phytochemical constituents for miscellaneous medicinal activities which are bioactive in nature. There is growing interest in the use of plants for the treatment and prevention of malaria. Medicinal plants are currently being evaluated as source of promising antimalaria agents. In this study, we have evaluated the claimed antimalarial properties of six extracts from three plants used in traditional medicine against malaria and we have investigated phytochemical screening. Schizontocidal activity was measured using a standard in vitro assay, with NF54 and K1 Plasmodium falciparum strain. From the 6 extracts tested, four of them showed a promising activity (5 ≤ IC50 ≤ 15 µg/mL). All extracts contained Polyterpenes and sterols, Polyphenols, Flavonoids and Alkaloids.
Pages: 358-360  |  637 Views  25 Downloads
How to cite this article:
Kipré Gueyraud Rolland, Offoumou Rostand M’Baï, Silué Kigbafori Dieudonné, Bouablé Guy Martial, Zirihi Guédé Noel, Djaman Allico Joseph. Antiplasmodial activity and phytochemical screening of Landolphia heudelotii, Mitragyna ledermannii and Spathodea campanulata, three traditional plants. J Pharmacogn Phytochem 2018;7(1):358-360.
Journal of Pharmacognosy and Phytochemistry