Pharmacognosy

Journal of Pharmacognosy and Phytochemistry

  • Printed Journal
  • Indexed Journal
  • Refereed Journal
  • Peer Reviewed Journal
Login

NAAS Rating: 5.21

updates
NAAS Rating: 5.21 new

Journal of Pharmacognosy and Phytochemistry

Vol. 7, Issue 1 (2018)

Toxicological and phytochemical studies of aqueous and ethanolic extracts of Entandrophragma angolense (Meliaceae), an antidiabetic plant of the Ivorian pharmacopoeia

Author(s): Kouamé Kouadio Degaulle, Doumbia Idrissa, Yeo Dodehe, Kipré Gueyraud Rolland, Koulaï Diane, Djaman Allico Joseph and N'guessan Jean David
Abstract: The purpose of this study was to evaluate the acute toxicity and to carry out the phytochemical study of aqueous and ethanolic extracts of Entandrophragma angolense (Meliaceae), a plant used in the traditional treatment of diabetes in the south-east of Cote d'Ivoire. The various tests carried out in the context of phytochemical screening was oriented towards the identification of the main chemical groups.To evaluate the toxicity, 60 wistar rats were divided into twenty groups containing three animals in each group. Mortality was observed after 24 hours while animal aspect and behavior changes were noted for 14 days. The acute toxicity study indicates that the extracts of Entandrophragma angolense have no toxicity at a dose of 5000 mg / kgwhile phytochemical screening revealed the following main groups: sterols, polyterpenes, polyphenols, flavonoids, tannins, quinones, alkaloids, saponosides
Pages: 2171-2174  |  401 Views  10 Downloads
How to cite this article:
Kouamé Kouadio Degaulle, Doumbia Idrissa, Yeo Dodehe, Kipré Gueyraud Rolland, Koulaï Diane, Djaman Allico Joseph, N'guessan Jean David. Toxicological and phytochemical studies of aqueous and ethanolic extracts of Entandrophragma angolense (Meliaceae), an antidiabetic plant of the Ivorian pharmacopoeia. J Pharmacogn Phytochem 2018;7(1):2171-2174.
Journal of Pharmacognosy and Phytochemistry