Materials and Methods: Different concentrations of tin leaf extract were tested with a radical compound of DPPH, with Vitamin C as a positive control. The inhibitory activity of AGEs compound formation was studied by reacting high concentrated sugar solution with protein in the form of Bovine Serum Albumin. With quercetin used as a positive control for barrier testing on the formation of AGEs. The reaction of tin leaf extract was determined by measuring the total content of the phenol compound using Folin-Ciocalteu reagent.

Results: The results showed that 96% of ethanol extract had a potent antioxidant activity, buthad little ability to inhibit AGEs. With IC₅₀ values of 55.38 μg/ml as an antioxidant and 750.29 μg/ml inhibiting AGEs, total phenol content of tin leaf extract was 0.71%.

Conclusion: Based on this information, it can be concluded that the 96% ethanol extract of tin leaf has a strong and an antioxidant activity. However it is in inhibiting AGEs compounds.