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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 3, Issue 4 (2014)

Isolation and Characterization of Potential Cytotoxic Leads from Ambrosia maritima L. (Asteraceae)

Author(s):

Amina Ibrahim Dirar, Magdi Awadalla Mohamed, Wadah Jamal Ahmed, Mona Salih Mohammed, Hassan Subki Khalid, Elrashied A. E. Garelnabi

Abstract:
Medicinal plants have long been recognized as an indispensable source for new leads. In this study, Ambrosia maritima L. (Asteraceae) was subjected to chromatographic (TLC & PTLC) and spectroscopic analysis (UV, IR, GC-MS & NMR) to isolate and elucidate its active constituents. Two promising antitumor leads namely; di(2-ethylhexyl) phthalate and 13-hexyloxacyclotridec-10-en-2-one, had been, unprecedentedly, isolated and characterized from the Brine shrimp Lethality Assay (BSLA) active dichloromethane extract.

Pages: 38-41  |  1766 Views  70 Downloads

How to cite this article:
Amina Ibrahim Dirar, Magdi Awadalla Mohamed, Wadah Jamal Ahmed, Mona Salih Mohammed, Hassan Subki Khalid, Elrashied A. E. Garelnabi. Isolation and Characterization of Potential Cytotoxic Leads from Ambrosia maritima L. (Asteraceae). J Pharmacogn Phytochem 2014;3(4):38-41.