Journal of Pharmacognosy and Phytochemistry
Vol. 3, Issue 5 (2015)
A new biologically active ecdysteroid from the aerial parts of Sida glutinosa
Niranjan Das, Tapasi Saha, Surajit Bhattacharjee
The aerial parts of Sida glutinosa have been analyzed for their chemical constituents, resulting in the isolation of a new ecdysone, named glutinosterone (1). The structure of glutinosterone was determined on the basis of extensive spectroscopic analysis, including 2D NMR data and the results of hydrolytic cleavage. The structure of glutinosterone was elucidated as 1Î²-hydroxy 24(28)-dehydromakisterone A. The in vitro biochemical analysis of compound 1 showed a significant effect on different enzymes involved in human liver function along with lipid metabolic enzymes. The compound 1 also exhibits moderate to significant anti-bacterial property.
Pages: 73-78 | 1561 Views 23 Downloads
Niranjan Das, Tapasi Saha, Surajit Bhattacharjee. A new biologically active ecdysteroid from the aerial parts of Sida glutinosa. J Pharmacogn Phytochem 2015;3(5):73-78.