• Printed Journal
  • Indexed Journal
  • Refereed Journal
  • Peer Reviewed Journal
Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 4, Issue 3 (2015)

The cytotoxic principle of Bejaria resinosa from Ecuador

Author(s):

Alírica I Suárez, Chabaco Armijos, José Miguel Andrade, Enrique V Quisatagsi, Marco Cuenca, Sandra Cuenca-Camacho, Natalia Bailon-Moscoso

Abstract:
Bejaria resinosa Mutis ex LF is also known as “pena de cerro” and is a plant species used traditionally by the Saraguro ethnic group in Ecuador to treat nervous system problems, swollen wounds and inflammations of the genital organs, as well liver diseases and cancer. The aim of this study was to screen Bejaria resinosa aqueous extract and isolated compounds from organic extracts, for activity against the following cancer cell lines: MCF-7 (breast carcinoma), PC-3 (prostate carcinoma), RKO (colon carcinoma), and D-384 (astrocytoma). This was followed by identification of the compounds responsible for this effect. The results indicated that ursolic acid is the principle active responsible for the cytotoxicity on tumor cells.

Pages: 268-272  |  1582 Views  136 Downloads

How to cite this article:
Alírica I Suárez, Chabaco Armijos, José Miguel Andrade, Enrique V Quisatagsi, Marco Cuenca, Sandra Cuenca-Camacho, Natalia Bailon-Moscoso. The cytotoxic principle of Bejaria resinosa from Ecuador. J Pharmacogn Phytochem 2015;4(3):268-272.