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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 5, Issue 1 (2016)

Antioxidant activity of silybin and 2,3-dehydrosilybin from Silybum marianum (L). Gaertn. Fruits

Author(s):

Vladimir A. Kurkin

Abstract:
Silybin (1) and 2,3-dehydrosilybin (2) were isolated from fruits of milk thistle [Silybum marianum (L). Gaertn.] сultivated in the Samara region (Russian Federation). 2,3-dehydrosilybin for the first time is described for the given plant, cultivated in Russian Federation. Silybin and 2,3-dehydrosilybin and also the fluid extract of Silybum marianum fruits (the ratio of the fruits and 80% ethanol is 1:1) have expressed antioxidant activity, decreasing the level of the lipid peroxidation caused FeSO4 in the homogenate of the liver rats. The antioxidant activity of 2,3-dehydrosilybin is reported for the first time and on 14,0% above those of silybin.

Pages: 256-259  |  1334 Views  46 Downloads

How to cite this article:
Vladimir A. Kurkin. Antioxidant activity of silybin and 2,3-dehydrosilybin from Silybum marianum (L). Gaertn. Fruits. J Pharmacogn Phytochem 2016;5(1):256-259.