The aim of the present study was to investigate the presence of major phytochemicals and the analgesic, antioxidant and thrombolytic effects of methanol extract of the seeds of a plant Pisum sativum
. Phytochemical analysis of the extract of Pisum sativum
seeds indicated the presence of Glycoside, Alkaloid, Flavonoids, Saponin and Tannin types of compounds. Significant analgesic effect was monitored (p
<0.05) as the oral extract dose of 500 mg/kg showed 42.75% inhibition of writhing movements compared to standard drug Diclofenac which inhibited 74.20% writhing movement. Also in present study the methanol extract of Pisum sativum
seeds have mild antioxidant activity. The IC50
of the extraction was 489.25 Âµg/ml, whereas IC50
of reference anti-oxidative agent Ascorbic acid was 16.28 Âµg/ml. Pisum sativum
extracts showed thrombolytic activity of (18.25 Â± 0.04%) comparing with standard Streptokinase (66.98 Â± 0.11%).
Amer Khorshed Alam and Chand Sultana Khatun. Phytochemical analysis and antioxidant, analgesic and thrombolytic activity investigation of methanol extract of Pisum sativum seed. J Pharmacogn Phytochem 2016;5(6):366-370.