The roots and steam barks of Ceiba pentandra
and Anogeissus leiocarpus was prepared by extracting 100g of the crude sample using the hot soxhlet extraction with n-hexane, ethyl acetate, acetone, methanol and water sequentially in order of their polarity index. The extracts were tested against some clinical isolates of Eschericia coli, Staphylococcus aureus, Aspergillus niger and Candida albicans. The results showed that the water stem bark extracts of Anogeissus leiocarpus W(S) B showed the highest activity with 20.00ug/ml, while the Acetone roots of Anogeissus leiocarpus extracts A(R)B had the least activity with 0.00mg/ml. in case of the antibacterial activity while in the case of the antifungal activity the water stem extracts of Ceiba pentandra
had the highest activity with 15.00ug/ml, while the Acetone roots of Anogeissus leiocarpus, methanol roots of extracts of Ceiba pentandra
A(R)B, M(R)A and W(R)A had the least activity of 0.00, 0.00, and 0.00 ug/ml antifungal activity. Streptomycin was used as the standard for the antibacterial activity while Fulcin was used as the standard for the antifungal activity. The antimicrobial activity of the roots and stem barks of Ceiba pentandra
and Anogeissus leiocarpus justifies the claims by the traditional healers that the roots and stem barks of the plants in used to cure different ailments.
Labaran A Magashi and Nuhu I. Antimicrobial activity of the roots and stem bark of Ceiba pentandra and Anogeissus leiocarpus grown in Bauchi, North Eastern Nigeria. J Pharmacogn Phytochem 2017;6(5):865-870.