Journal of Pharmacognosy and Phytochemistry
Vol. 6, Issue 5 (2017)
Percentage yield and acute toxicity of the plant extracts of Ceiba pentandra grown in Bauchi State, North Eastern Nigeria
Abubakar EM, Modibbo S Misau and Lamaran Bala G
The roots and stem bark of Ceiba pentandra
was subjected to hot Soxhlet extraction using solvent of different polarity, hexane, ethyl acetate, acetone, methanol and water. The methanol extracts gave the highest yield of 17.5% highest polar solvent while hexane being the lowest polar solvent gave the least percentage recovery of 1.12%. The colour and texture of each of the extract was also determined. Hexane and ethyl acetate extract showed yellow and orange colour, with the texture oily and solid. While acetone, methanol and water extracts gave brown and dark brown colour with the texture being solid and pastry. The acute toxicity of the extracts was also determined by using both the oral and intraperitoneally dosage concentration. The intraperitoneally dosage with slight modification tends to be toxic than the oral dosage.
Pages: 1777-1779 | 504 Views 17 Downloads
Abubakar EM, Modibbo S Misau and Lamaran Bala G. Percentage yield and acute toxicity of the plant extracts of Ceiba pentandra grown in Bauchi State, North Eastern Nigeria. J Pharmacogn Phytochem 2017;6(5):1777-1779.