Volume 2, Issue 2


Ubiquitous Ursolic Acid: A Potential Pentacyclic Triterpene Natural Product


Author(s): Ibrahim T Babalola 1,2*, Francis O. Shode 2

1. Department. of Chemistry, Faculty of Science, Yobe State University, PMB 1144 Damaturu, Nigeria
2. Department of Chemistry, Faculty of Sciences and Agriculture, University of Zululand, Private Bag X1001, KwaDlangezwa 3886, Republic of South Africa and Research, Innovation & Development Director of Life-Promoters Biosciences (Pty) Ltd, 5 Ferrara Gardens, Westville North 3629, South Africa.

Abstract: There is an unprecedented growing interest in natural triterpenes in the last few decades due to the discovery of their potential biological and pharmacological activities.  Ursolic acid (3β-hydroxyurs-12-en-28-oic) (UA) (4) is a pentacyclic triterpene, occurring in many plant parts including fruits and seeds. This paper reviews several studies on the in vitro and in vivo pharmacological activities of UA (4). This review brings to limelight sources and the beneficial potentials of UA (4) in foods, cosmetics and medicine.

Related Graphics:

Biosynthesis of ursolic acid (4) and oleanolic acid (5) from oleanyl cation


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