Journal of Pharmacognosy and Phytochemistry

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Journal of Pharmacognosy and Phytochemistry

Vol. 6, Issue 3 (2017)

In vitro antifungal activity of essential oils extracted from some plants of Tangawisi® products on Candida albicans

Author(s): Vawazola Nsimaketo Victor Héritier, Mutwale Kapepula Paulin, Ngombe Kabamba Nadège, Mpuza Kapundu Michel and Masimango Ndyanabo Jude-Thaddée
Abstract: This work aimed to evaluate the antifungal activity of essential oils extracted from Tangawisi® plants on a strain of Candida albicans. Nine plants were identified as aromatic plants contained in Tangawisi® products and their essential oil yield had being determined. The extraction yield in essential oils of identified plants were respectively Piper guineense (4.94%), Monodora myristica (1.57%), Zingiber officinalis (1.31%), Xylopia aethiopica (1.23%), Securidaca longepedunculata (1.07%), Cyperus articulatus (0.59%), Aframomum melegueta (0.33%), Mangifera indica (0.16%) and Heinsia crinita (0,247%). TLC chromatographic profile showed that each essential had a characteristic fingerprint and compared to thymol and eugenol used as positive control, only Zingiber officinalis contains eugenol. The diameter of the inhibition zone formed as a result of six of these essential oils is 6 mm for essential oils of Monodora myristica and Piper guineense, 9.33 mm for that of Cyperus articulatus, 11.33 mm for the Xylopia aethiopica, 15.7 mm for that of Securidaca longepedunculata and 19 mm for the Zingiber officinalis oils. The minimum fungistatic concentration on the strain of Candida albicans is 0.05% for essential oils of Securidaca longepedunculata, 0.075% for Zingiber officinalis and Xylopia aethiopica and 0.5% for those of Monodora myristica, Piper guineense and Cyperus articulatus. The essential minimum fungicidal concentration is 0.075% for oil of Securidaca longepedunculata, 0.25% for that of Zingiber officinalis, 0.5% for that of Xylopia aethiopica, 1% for that of Monodora myristica, 2.5% for that of Cyperus articulatus and is greater than 3.5% for that of Piper guineense. The essential oils of Securidaca longepedunculata, Zingiber officinalis and Monodora myristica have a fungicide power to the Candida albicans strain while those of Xylopia aethiopica, Cyperus articulatus and Piper guineense have a fungistatic one.
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