Author(s):

Abbas AY, Muhammad FI, Dallatu MK, Abubakar AL and Sahabi SM

Abstract:
Liver disease is still a worldwide problem. Cassia arereh is one out of many medicinal plants in Northern Nigeria used for the management of liver diseases. The study was designed to evaluate the hepatoprotective effects of Cassia arereh against CCl₄ - induced liver damage in rats. Standard analytical methods were employed in all the parameters assessed. Administration of methanolic leaves extract of C. arereh at doses of 50, 100, 150, 200 mg/kg body weight significantly(P<0.05) reduced the elevated serum liver marker enzymes and lipid peroxidation index (Malondialdehyde) and also increased the levels of total protein, albumin and endogenous antioxidants when compared to CCl₄ – induced not treated group. The hepatoprotective effect observed might be due to its rich phytochemical constituents.

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