Journal of Pharmacognosy and Phytochemistry
Vol. 1, Issue 4 (2012)
In-Vitro Thrombolytic and Anti-inflammatory Activity of Swertia Chirata Ethanolic Extract.
Author(s):
Mohammad Shahadat Hossain*, Mohammad Ehsanul Hoque Chowdhury, Sumana Das and Imtiaz Uddin Chowdhury
Abstract:
Ethanol extract of of Swertia chirata was assessed for its thrombolytic, anti-inflammatory activity and phytochemical screening. In vitro anti-inflammatory activity was evaluated using albumin denaturation. Aspirin was used as a standard drug for the study of anti-inflammatory activity. The ethanol extract of Swertia chirata showed mean inhibition of protein denaturation 45.31±0.000576 whereas, for control group it was found to be 50.00±0.00177. In thrombolytic activity using in vitro clot lysis assay method, the crude ethanol extract was found to have significant, thrombolytic test showed a maximum effect of 40.38% while the standard streptokinase showed 69.35.
Pages: 99-104 | 3412 Views 649 Downloads
Mohammad Shahadat Hossain*, Mohammad Ehsanul Hoque Chowdhury, Sumana Das and Imtiaz Uddin Chowdhury. In-Vitro Thrombolytic and Anti-inflammatory Activity of Swertia Chirata Ethanolic Extract.. J Pharmacogn Phytochem 2012;1(4):99-104.