Author(s):

CHIBUEZE NWOSE

Abstract: The effect of ethanolic extract of fresh leaves of Kalanchoe pinnata on the level of cretatine kinase was investigated using albino rats. The extract with ethanol yielded 7.80%. The albino rats were treated with doses of 200mg/kg and 400mg/kg body weight of the extrat for seven days. Results showed that there was a slight decrease in physical activities and body weight of all the animals treated with the ethanolic extract compared to the control. There was a significant (P > 0.05) increase in serum creatine kinase activity in albino rats treated with the ethanolic extract than the control. Within the groups treated with the ethanolic extract, Group A (400mg/kg body weight) was significantly (P > 0.05) higher than Group B (200mg/kg body weight). This increase value of creatine kinase activity could encourage the supply of energy needed for muscular contraction.

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