Journal of Pharmacognosy and Phytochemistry
Vol. 1, Issue 6 (2013)
Screening of Analgesic and Immunomodulator activity of Artocarpus heterophyllus Lam. Leaves (Jackfruit) in Mice
Om Prakash, Jyoti, Amit Kumar, Pawan Kumar
Adaptability is probably the most distinct characteristics of life which may be defined as sum of all nonspecific response of the body to any demands made upon it; fundamentally it was a physiological response; primary object of which was to maintain life and to re-establish the normal state. Analgesic and Immunomodulator activity of leaves of Artocarpus heterophyllus Lam. was evaluated by using Eddyâ€™s hot plate method and Swimming endurance test at the dose levels of 250 and 500mg/kg in Swiss albino mice respectively. The methanolic and aqueous extracts of leaves of A. heterophyllus were administered to the experimental animals among which the methanolic extract of A. heterophyllus leaves have shown to be exhibit significant analgesic and immunomodulator effect by paw licking and increasing the swimming or survival time (P<0.001) respectively in mice.
Pages: 33-36 | 2480 Views 458 Downloads
Om Prakash, Jyoti, Amit Kumar, Pawan Kumar . Screening of Analgesic and Immunomodulator activity of Artocarpus heterophyllus Lam. Leaves (Jackfruit) in Mice. J Pharmacogn Phytochem 2013;1(6):33-36.