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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 2, Issue 1 (2013)

Hepatoprotective and Antioxidant effect of Polygala rosmarinifolia Wight & Arn against CCl4 induced hepatotoxicity in rats.

Author(s):

M. Alagammal, M. Packia Lincy and V.R. Mohan*

Abstract:
Carbon tetrachloride (CCl4) intoxicated rats showed significant elevation in serum enzymes, bilirubin and lipid peroxidation of the liver tissues and reduction in serum total protein, superoxide dismutase, catalase, reduced glutathione peroxide activity. Treatment with ethanol extract of Polygala rosmarinifolia whole plant altered the above parameters to the levels of near normal. All the above results were comparable with the standard drug silymarin (100mg/kg) treated group. Thus the present study ascertains that the ethanol extract of Polygala rosmarinifolia whole plant possesses significant hepatoprotective activity.

Pages: 118-124  |  1533 Views  28 Downloads

How to cite this article:
M. Alagammal, M. Packia Lincy and V.R. Mohan*. Hepatoprotective and Antioxidant effect of Polygala rosmarinifolia Wight & Arn against CCl4 induced hepatotoxicity in rats.. J Pharmacogn Phytochem 2013;2(1):118-124.