Author(s):

Jitendra Modi, Hardik Soni, Kruti Pandya, Ghanshyam Patel, Nikunjana Patel

Abstract: Herbal formulations have reached extensive acceptability as therapeutic agents for several diseases. The development of authentic analytical methods which can reliably profile the phytochemical composition, including quantitative analysis of the active compound and other major constituents, is a major challenge to scientists. Standardization is an important step for the establishment of a consistent biological activity, a consistent chemical profile, or simply a quality assured for the manufacturing of herbal drugs. The WHO specifies guidelines for the assessment of the safety, efficacy and quality of herbal medicines as a prerequisite for global harmonization. Present study was focused on an exhaustive standardization of Herbo-mineral syrup preparation Zeal Cough Syrup which was carried out employing the basic organoleptic test, physico-chemical tests, and bio-assays by sophisticated instruments like HPLC, HPTLC. HPTLC fingerprinting, assays of marker compounds etc. were carried out to confirm their quality and potency. The presence of the raw materials in the finished product was carried out with the aid of sophisticated instruments. The study results revealed that the syrup formulation was well standardized at various levels such as Physical consistency, Chemical profile, Microbial and Heavy metal limits.

Pages: 36-42  |  3446 Views  571 Downloads

Download (309KB)