Author(s):

Hina Rehman, Wajeeha Begum, Farzana Anjum, Humyra Tabasum

Abstract: Rheum emodi or Himalayan rhubarb is a perennial herb belongs to family Polygonaceae. It has been used in various traditional systems as laxative, tonic, diuretic and to treat fever, cough, indigestion, menstrual disorder since antiquity. This paper consists of literature of Rheum emodi regarding its ethnobotany, folkloric uses, chemical properties and pharmacological studies. The material was collected from journals and books via library and electronic search. The most common constituents of Rheum emodi are anthraquinone (rhein, chrysophanol, aloe-emodin, emodin, physcion, and their glycosides) and stilbene (picetannol, resveratrol and their glycosides). Studies have shown that Rheum emodi possess anticancer, antioxidant, anti-inflammatory, antimicrobial, antifungal, antidyslipidemic, antiplatelet, antidiabetic, antiulcer, hepatoprotective, immunoenhancing and nephroprotective activities. These studies raised the therapeutic efficacy of rhubarb in diverse ailments. It is essential that this drug should studied more extensively to confirm these therapeutic effects and to validate traditional uses.

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