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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 4, Issue 2 (2015)

Characterization and evaluation in vitro of the antibacterial activity of tannins from Garcinia brevipedicellata (Bark.G) Hutch. & Dalz

Author(s):

Ngoupayo Joseph, Chelea Matchawe, Djiele Ngameni Patrice, Félicien Mushagalusa Kasali, Ndjonkep Joe Yann, Fotsing Kwetche Pierre René, Ndelo Josaphat

Abstract:
The present study was conducted to evaluate the effectiveness of the tannic extract of Garcinia brevipedicellata, a plant used in Cameroon medicinal traditional, in treatment of bacterial infectious including food infections. The phytochemical characterization of tannins focused on the classic methods of screening. The macrodilution in liquid medium for 24 hours (acetone/water) allowed evaluating its antibacterial activity on the Escherichia coli, Klebsiella pneumonia, Salmonella Typhimurium, Staphylococcus aureus and Vibrio cholera, microbial strains. The phytochemical characterization was positive. The best inhibitory activity was obtained with Salmonella Typhimurium at 12.5mg/mL of MIC, with a ratio MIC/MBC of 2, and the best bactericidal activity on Klebsiella pneumonia at 50 mg/mL of MBC; with a ratio MBC/MIC ≤ 4. The minimal inhibitory and bactericidal concentrations vary between 50 and 200 mg/mL. The present study revealed the antimicrobial potentials of tannic extract of Garcinia brevipedicellata on some microbial strains. A thorough study would be desirable for future use as a phytomedicine. Antibacterial activity, tannic extracts, minimal inhibitory and bactericidal concentrations, Garcinia brevipedicellata.

Pages: 81-85  |  1599 Views  42 Downloads

How to cite this article:
Ngoupayo Joseph, Chelea Matchawe, Djiele Ngameni Patrice, Félicien Mushagalusa Kasali, Ndjonkep Joe Yann, Fotsing Kwetche Pierre René, Ndelo Josaphat. Characterization and evaluation in vitro of the antibacterial activity of tannins from Garcinia brevipedicellata (Bark.G) Hutch. & Dalz. J Pharmacogn Phytochem 2015;4(2):81-85.