Journal of Pharmacognosy and Phytochemistry
Vol. 4, Issue 2 (2015)
Formulation and evaluation of a photoprotectant cream containing Phyllanthus emblica extract-phospholipid complex
Alisha Pereira, Rashmi Mallya
Photoprotectives in skin-care is essential to prevent oxidative stress induced by long term exposure to UV. Phyllanthus emblica fruit extract contains polyphenols that are potent antioxidants. But polyphenols have limited penetration into skin therefore its topical use, as a photoprotectant, is ineffective. This study aims to develop a phospholipid complex of amla extract that enhances the delivery of polyphenols into the skin. The amla extract phospholipid developed, had an entrapment efficiency of 94.03Â±0.10 %. The characterization studies showed that constituents of amla extract successfully formed a complex with phospholipids. The complex was incorporated into a cream formulation, which was found to be stable. The ex-vivo diffusion studies of cream showed that administration of the amla extract via phospholipid complexes gave better skin retention compared to the conventional cream. Thus, phospholipid complex of amla extract gave a prolonged antioxidant effect compared to the conventional cream.
Pages: 232-240 | 2650 Views 731 Downloads
Alisha Pereira, Rashmi Mallya. Formulation and evaluation of a photoprotectant cream containing Phyllanthus emblica extract-phospholipid complex. J Pharmacogn Phytochem 2015;4(2):232-240.