Author(s):

Firoj A Tamboli, Harinath N More

Abstract: We evaluated anthelmintic activity of aqueous and ethanolic extracts of leaves of Barleria gibsoni Dalz. (Acanthaceae) and experiment was carried out against Indian adult worm Pheretima posthuma. Various concentrations (5-15mg/ml) aqueous and ethanolic extracts were evaluated in the bioassay involving determination of time of paralysis (P) and time of death (D) of the worms. Albendazole (Std.) was used as standard anthelmintic drug and distilled water was used as control. The results of present study indicated that the ethanolic and aqueous extracts significantly exhibited paralysis (P<0.01) in worms in lower doses (5, 10 and 15 mg/ml) and also caused death of worms especially at higher concentration of 15mg/ml, as compared to standard drug. Further studies are in process to isolate the active principles responsible for the anthelmintic activity.

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