Samuel E Okhale, Edifofon Akpan, Omolola Temitope Fatokun, Kevwe Benefit Esievo, Oluyemisi Folashade Kunle
, also known as wild custard apple and wild soursop is a member of Annonaceae family. It is a fruit tree native to Senegal and found in semi-arid to subhumid regions of Africa, with a long history of traditional use. Numerous ethnomedicinal uses have been attributed to different parts of A. senegalensis
, as well as its use as food and food additives. All parts of the plant contain varying amounts of essential oils. Annogalene, annosenegalin, acetogenins, kaurenoic acid and (-)-roemerine are the major bioactive constituents of A. senegalensis
. Biological activities of phytoconstituents from various parts of A. senegalensis
include anticonvulsant, cytotoxic, antimicrobial, antispasmodic, anti-inflammatory and analgesic activities; others are antioxidant, antivenomous, hypnotic, anthelmintic, antiplasmodial, haemostatic, spermatogenic and insecticidal activities.
Samuel E Okhale, Edifofon Akpan, Omolola Temitope Fatokun, Kevwe Benefit Esievo, Oluyemisi Folashade Kunle. Annona senegalensis Persoon (Annonaceae): A review of its ethnomedicinal uses, biological activities and phytocompounds. J Pharmacogn Phytochem 2016;5(2):211-219.