NgaÃ¯ssona P, Nkounkou Loumpangou C, Namkona FA, Koane JN, Gouollaly Tsiba, Syssa-MagalÃ© JL and Ouamba JM
Stapf., synonymous Tabernaemontana nitida known under the vernacular name of "NgongabÃ©" is a medicinal plant of the family of Apocynaceae, widely used in Central African traditional medicine. This study is a contribution to the phytochemical screening and evaluation of the antioxidant activity of this species. Preliminary phytochemical tests conducted on various crude extracts of P. nitida
have revealed the presence of some chemical groups: alkaloids, flavonoids, tannins, saponins, triterpenes and sterols. The estimate of the content of total phenols and flavonoids by calorimetric methods showed that the extracts methanolic, hydro-methanolic and aqueous of bark of trunk and root of Picralima nitida
Stapf., showed that the extracts are rich in these compounds. The evaluation of the antiradical capability realized by the DPPH test on TLC plate on the one hand, and by the method of trapping of the free radical DPPH on microplate 96 wells, revealed that the various extracts of P. nitida
respectively have a moderated reduction (2, 867 Â± 0,002 mg/mL, 3,161 Â± 0,016 mg/mL and 2,693 Â± 0,004 mg/mL) for the extracts methanolic, hydro-mÃ©thanolic and aqueous, but relatively low compared to the molecule of reference, the ascorbic acid (0,064 Â± 0,000 mg/mL).
NgaÃ¯ssona P, Nkounkou Loumpangou C, Namkona FA, Koane JN, Gouollaly Tsiba, Syssa-MagalÃ© JL and Ouamba JM. Phytochemical screening and evaluation of the antioxidant activity of the polar extracts Picralima nitida Stapf. (Apocynaceae) family. J Pharmacogn Phytochem 2016;5(4):198-204.